Question · Rejuran

How long does Rejuran last?

There is no single fixed number. Rejuran is usually a course of sessions that build and maintain a skin-quality effect. How long it appears to last depends on the person, the product, and the number and spacing of sessions — so ask your clinician for a realistic maintenance interval.

Last reviewed: 16 Aug 2026

Key takeaways
  • Usually a course, not a one-time fix
  • Duration depends on product, sessions and skin
  • Maintenance sessions extend the effect
  • Ask for a realistic maintenance interval

There is no single fixed number. Rejuran is usually approached as a course of sessions that build and then maintain a skin-quality effect, rather than a one-time treatment with a fixed expiry. How long the effect appears to last depends on the individual, the specific product, the number and spacing of sessions, and the person's baseline skin condition.

Many clinics discuss an initial series followed by periodic maintenance. Because protocols and products differ, the most useful question is not "how many months" in the abstract, but "what maintenance interval do you recommend for my skin and plan?"

What affects how long it lasts

  • Number and spacing of sessions in the initial course
  • The specific polynucleotide product and concentration used
  • Your baseline skin quality, age and lifestyle factors
  • Whether maintenance sessions are continued
Evidence notePolynucleotide boosters are described in dermatology literature as promising for skin quality, but protocols and durability outcomes are heterogeneous and still being standardised. Treat any single "lasts X months" claim with caution and confirm with a clinician.

Common questions

How many Rejuran sessions are needed?
Often an initial series followed by maintenance, but the exact number depends on your skin and the clinic's protocol.
Is Rejuran permanent?
No skin booster is permanent. It supports skin quality over time and is maintained with periodic sessions.
What is the downtime after Rejuran?
Injection papules, swelling or bruising can occur and usually settle within days. Confirm expected downtime before a trip.

Continue exploring

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